| Name |
FSSP |
 |
| Status |
The current release has 2860
entries and was indexed 23-Mar-2006.
|
| Description |
FSSP (families of structurally similar proteins) is a database of
structural alignments of proteins in the Protein Data Bank (PDB)
[1]. The database currently contains an extended structural family for
each of 330 representative protein chains. Each data set contains
structural alignments of one search structure with all other
structurally significantly similar proteins in the representative set
(remote homologs, below 30%% sequence identity), as well as all structures
in the Protein Data Bank with 70-30%% sequence identity relative to
the search structure (medium homologs). Very close homologs (above 70
% sequence identity) are excluded as they rarely have marked
structural differences. The alignments of remote homologs are the
result of pairwise all-against-all structural comparisons in the set
of 330 representative protein chains. All such comparisons are based
purely on the 3D co-ordinates of the proteins and are derived by
automatic (objective) structure comparison programs. The significance
of structural similarity is estimated based on statistical
criteria. The FSSP database is available electronically from the EMBL
file server and by anonymous ftp (file transfer protocol).
|
| Literature |
[1] Holm, L., Ouzounis, C., Sander, C., Tuparev, G., Vriend, G. (1992).
"A database of protein structure families with common folding motifs."
Protein Science 1, 1691-1698.
|
| WWW |
http://www.sander.ebi.ac.uk/dali/fssp/
|
| Data-fields in SRS |
|
| Loaders |
|
| Links |
|
| SRS Description |
Structure
(
srsgen.i
,
srsdb.i
,
href.i
)
Syntax
Information
|